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Learn about magnesium hydroxide mixture, its preparation, properties, medicinal uses, and benefits. Discover how it works as an antacid and laxative for digestive relief.
Introduction
Magnesium hydroxide mixture is a widely used antacid and laxative, known for its ability to neutralize stomach acid and relieve constipation. It is commonly found in pharmaceutical formulations such as Milk of Magnesia, which provides gentle relief from acid indigestion and bowel irregularities.
This article explores the preparation, properties, and medicinal uses of magnesium hydroxide mixture, along with its benefits and potential side effects.
Preparation of Magnesium Hydroxide Mixture
Magnesium hydroxide mixture is prepared by precipitation of magnesium salts with an alkaline solution, followed by suspension in water to create a stable liquid form.
Method of Preparation
1. Dissolve magnesium sulfate (MgSOâ‚„) or magnesium chloride (MgClâ‚‚) in distilled water.
2. Add sodium hydroxide (NaOH) or lime water (Ca(OH)â‚‚) slowly while stirring.
3. Magnesium hydroxide (Mg(OH)â‚‚) precipitates out as an insoluble, milky-white suspension.

4. The precipitate is washed, filtered, and suspended in purified water to create a smooth, stable mixture.
Properties of Magnesium Hydroxide Mixture
Chemical Formula: Mg(OH)â‚‚
Molecular Weight: 58.32 g/mol
Appearance: White, milky suspension
Solubility: Insoluble in water but dissolves in acids
pH: Alkaline (pH ~10) when in suspension
Taste: Mild, slightly bitter
A magnesium hydroxide mixture is a low-solubility compound, meaning it remains in suspension rather than dissolving, which makes it gentle on the stomach.
Medicinal Uses of Magnesium Hydroxide Mixture
1. Antacid for Acid Reflux and Indigestion: Neutralizes excess stomach acid, providing relief from heartburn, gastritis, and acid reflux.Works faster than aluminum-based antacids, making it an effective choice for quick relief.
2. Laxative for Constipation Relief: Acts as an osmotic laxative, drawing water into the intestines, softening stools, and promoting bowel movements. Used in conditions like occasional constipation and post-surgical bowel regulation.
3. Bowel Preparation Before Medical Procedures: Used in higher doses to clear the bowel before diagnostic procedures like colonoscopy.
4. Alkalizing Agent in the Body: Helps neutralize excess acidity in certain metabolic disorders.
5. Topical Use for Skin Conditions: Used in creams and lotions for minor burns, rashes, and insect bites due to its soothing and anti-inflammatory properties.
Benefits of Magnesium Hydroxide Mixture
- – Fast-acting antacid with mild laxative effects.
- – Gentle on the stomach, does not cause gas formation.
- – Non-habit forming when used as a laxative.
- – Does not interfere significantly with nutrient absorption.
Side Effects and Precautions
While generally safe, excessive or prolonged use may cause:
1. Diarrhea: Due to its laxative action, overuse can cause dehydration.
2. Electrolyte imbalance: Long-term use can affect potassium and sodium levels.
3. Magnesium Toxicity (Hypermagnesemia): More common in kidney patients, leading to weakness, low blood pressure, and confusion.
4. Drug Interactions: These may interfere with the absorption of antibiotics, iron, and certain medications.
Precaution: Patients with kidney disease or electrolyte imbalances should consult a doctor before using magnesium hydroxide regularly.
Conclusion
Magnesium hydroxide mixture is a safe and effective antacid and laxative, widely used for acid reflux, constipation relief, and bowel cleansing. It provides gentle and rapid relief but should be used cautiously in individuals with kidney disease or electrolyte imbalances. Its dual action as an antacid and laxative makes it a valuable addition to gastrointestinal treatments.
Frequently Asked Questions (FAQs)
1. How does magnesium hydroxide relieve constipation?
Answer: It draws water into the intestines, softening stools and promoting natural bowel movements.
2. Can magnesium hydroxide be used daily?
Answer: Occasional use is safe, but long-term use can cause electrolyte imbalances and dependence.
3. What is the difference between magnesium hydroxide and aluminum hydroxide?
Answer: Magnesium hydroxide acts faster but may cause diarrhea, while aluminum hydroxide is slower but may cause constipation.