Chemical Degradation of Penicillins
by Meta Description Learn about the chemical degradation of penicillins, including factors affecting stability, degradation pathways, and their impact on drug efficacy. Introduction The chemical degradation …
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Penicillin: Definition, Background, Nomenclature, and Mechanisms
Penicillin, the most important antibiotic, was first extracted from the mould Penicillium notatum. Subsequently, a mutant of a related mould, P. chrysogenum, was found to …
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β-Lactam antibiotics: Definition, Mechanism and Types
Beta-lactam antibiotics are a class of antibiotics characterized by the presence of a beta-lactam ring in their molecular structure. This ring is crucial for its …
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Antibiotics: Historical background and Classification
INTRODUCTION Antibiotics, also known as antimicrobial agents, are medications that destroy or slow down the growth of other species of microorganisms. They include a range …
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GPAT 2024: Registration Dates, Admit Card, Eligibility, Pattern & Syllabus
The GPAT Exam 2024, administered by the National Board of Examinations in Medical Sciences (NBEMS), is a national-level test for admission to Pharmacy (PG) courses. …
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Bioisosterism
Bioisosters are substituents or groups with similar physical or chemical properties that produce broadly similar biological properties to other chemical compounds. The relation between bioisosteres …
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Drug metabolism or Bio-transformation
Drug metabolism refers to the biochemical processes by which the body chemically modifies pharmaceutical compounds to make them more water-soluble and easier to eliminate from …
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Stereoisomerism of drugs
Stereochemistry involves the study of the three-dimensional nature of molecules. It is the study of the chiral molecules. Conformational Isomers: Different arrangements of atoms that …
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PHYSIOCHEMICAL PROPERTIES IN RELATION TO BIOLOGICAL ACTION
The various physiochemical properties affecting the drug action are- 1. Ionization 5. Protein bonding 2. Solubility 6. Chelation 3. Partition coefficient 7. Bioisosterism …
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Structure of Biological Membrane
The biological membrane (or cell membrane and plasma membrane) is a selectively permeable membrane that allows only certain substances to pass through it and acts …