β-Lactam antibiotics: Definition, Mechanism and Types
by Beta-lactam antibiotics are a class of antibiotics characterized by the presence of a beta-lactam ring in their molecular structure. This ring is crucial for its …
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Antibiotics: Historical background and Classification
INTRODUCTION Antibiotics, also known as antimicrobial agents, are medications that destroy or slow down the growth of other species of microorganisms. They include a range …
GPAT 2024: Registration Dates, Admit Card, Eligibility, Pattern & Syllabus
The GPAT Exam 2024, administered by the National Board of Examinations in Medical Sciences (NBEMS), is a national-level test for admission to Pharmacy (PG) courses. …
Bioisosterism
Bioisosters are substituents or groups with similar physical or chemical properties that produce broadly similar biological properties to other chemical compounds. The relation between bioisosteres …
Drug metabolism or Bio-transformation
Drug metabolism refers to the biochemical processes by which the body chemically modifies pharmaceutical compounds to make them more water-soluble and easier to eliminate from …
Stereoisomerism of drugs
Stereochemistry involves the study of the three-dimensional nature of molecules. It is the study of the chiral molecules. Conformational Isomers: Different arrangements of atoms that …
PHYSIOCHEMICAL PROPERTIES IN RELATION TO BIOLOGICAL ACTION
The various physiochemical properties affecting the drug action are- 1. Ionization 5. Protein bonding 2. Solubility 6. Chelation 3. Partition coefficient 7. Bioisosterism …
Structure of Biological Membrane
The biological membrane (or cell membrane and plasma membrane) is a selectively permeable membrane that allows only certain substances to pass through it and acts …
HISTORY AND DEVELOPMENT OF MEDICINAL CHEMISTRY
Medicinal chemistry roots can be found in the fertile mix of ancient folk medicine and early natural product chemistry, hence its name. As appreciation for …
Agonist and Antagonist
An agonist and an antagonist are two types of molecules that interact with receptors in the body, but they have opposite effects on the receptor …