by Bromodiphenhydramine is a diphenhydramine derivative, an antihistamine used to treat allergy symptoms. As the name suggests, Bromodiphenhydramine contains a bromine atom in its structure. Adding bromine is a chemical modification intended to alter the properties or enhance the effects of the original diphenhydramine compound.
Structure
Synthesis
Mechanism of action
Bromodiphenhydramine competes with free histamine for binding at HA-receptor sites, thereby antagonizing the effects of histamine on HA-receptors. This competition results in a decrease in the negative symptoms induced by histamine HA-receptor binding.
Properties and uses:
It is effective for mild, local allergic reactions, physical allergies, and minor drug reactions characterized by pruritus.
Dose:
The usual dose is 25 mg three or four times per day.
